Novel therapy for the treatment of hyperphosphataemia
Specialty pharmaceutical company focused on the development and commercialisation of mineral-derived, late-stage, hospital-focused pharmaceuticals that address areas of high unmet medical need.
Lead product PT20
PT20 is a novel oral ferrihydrite based therapy for the treatment of hyperphosphataemia associated with end-stage renal disease. Hyperphosphataemia is a life-threatening complication of chronic kidney disease (CKD), the incidence of which is itself increasing across the world as obesity levels rapidly rise.
Ongoing development
PT20 acts as a ‘phosphate sponge’ and data from early studies suggest it exhibits higher binding capacity than market leading phosphate binders due to changes in the ferrihydrite crystal structure following a proprietary manufacturing process.
In addition, the low systemic absorption and the well-tolerated nature of ferrihydrite indicate that a very good side effect profile should be expected.